If your filament is not smooth (equal radius throughout the roll) it is likely bad. It could have been a bad extrusion when the filament was created. Picture?
It does seem it is a bad extrusion when made. I’ll try to get a pic when I can. In the meantime it is like little bumps on one side or 1 quarter side. At first I thought it was teeth marks when I felt it but I ruled that out as it seems to go for a long time and really does look like little bumps or blisters.